Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macAPutative HlyD family secretion protein; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (416 aa)    
Predicted Functional Partners:
macB
Hypothetical protein; ABC-type antimicrobial peptide transport system permease component.
 
 
 0.960
sce4823
ABC transporter, ATP-binding protein.
 
 
 0.945
sce7228
Hypothetical protein; ABC-type antimicrobial peptide transport system permease component.
 
 
 0.832
salY
Hypothetical protein; ABC-type antimicrobial peptide transport system permease component.
 
 
 0.832
sce1005
Macrolide-specific ABC-type efflux carrier; Family membership.
 
 
 0.831
sce1006
Hypothetical protein; ABC-type antimicrobial peptide transport system permease component.
 
 
 0.831
sce4825
Probable outer membrane protein; Family membership.
  
 
 0.814
macB-2
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.812
sce1003
ABC transporter, ATP-binding protein; Family membership.
 
 
 0.802
sce8833
ABC transporter, ATP-binding protein.
 
 
 0.724
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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