Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hgoHomogentisate 1,2-dioxygenase; High confidence in function and specificity. (386 aa)    
Predicted Functional Partners:
hppD1
4-hydroxyphenylpyruvate dioxygenase; Family membership.
 
 0.998
hppD2
4-hydroxyphenylpyruvate dioxygenase; Family membership.
 
 0.993
sce5978
Putative glutathione-S-transferase; Family membership.
 
 
 0.963
uptA
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; Family membership.
 
  
 0.936
sce5980
Homogentisate 1,2-dioxygenase; Family membership.
  
  
 
0.900
phhA
Phenylalanine 4-monooxygenase; Family membership.
 
  
 0.853
sce1872
Unnamed protein product; Family membership.
 
 
 0.747
sce5977
Putative fumarylacetoacetate hydrolase family protein; Family membership.
 
  
 0.731
epi
Methylmalonyl-CoA epimerase; High confidence in function and specificity.
  
 
 0.707
sce7240
Fumarylacetoacetate hydrolase family protein.
 
  
 0.658
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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