Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
uptA2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; Family membership. (325 aa)    
Predicted Functional Partners:
sce5978
Putative glutathione-S-transferase; Family membership.
 
 0.986
hgo
Homogentisate 1,2-dioxygenase; High confidence in function and specificity.
 
  
 0.936
hppD1
4-hydroxyphenylpyruvate dioxygenase; Family membership.
 
  
 0.917
sce5977
Putative fumarylacetoacetate hydrolase family protein; Family membership.
  
  
 
0.900
fumC1
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.815
fumC2
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.815
sdhA1
Succinate dehydrogenase; High confidence in function and specificity.
  
 
  0.814
sdhA2
Succinate dehydrogenase; High confidence in function and specificity.
  
 
  0.814
sdhB1
Succinate dehydrogenase; High confidence in function and specificity.
  
 
  0.807
sdhB2
Succinate dehydrogenase; High confidence in function and specificity.
  
 
  0.807
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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