Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sce5007Putative Aldehyde dehydrogenase (NAD(+)); Family membership; Belongs to the aldehyde dehydrogenase family. (464 aa)    
Predicted Functional Partners:
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.922
gabT2
4-aminobutyrate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.920
gabT1
4-aminobutyrate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.919
sce9190
Putative 4-aminobutyrate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.917
sce9194
4-aminobutyrate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.917
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.915
yahK
Alcohol dehydrogenase; High confidence in function and specificity.
  
 0.914
adh2
Class III alcohol dehydrogenase; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.914
adh5
Alcohol dehydrogenase; High confidence in function and specificity.
  
 0.914
sce6911
Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Family membership; Belongs to the arginase family.
  
 
 0.912
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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