| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dprA | gid | sce5116 | sce5114 | DNA processing chain A; High confidence in function and specificity. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.536 |
| dprA | sce5117 | sce5116 | sce5117 | DNA processing chain A; High confidence in function and specificity. | No similarity. | 0.714 |
| dprA | sce5118 | sce5116 | sce5118 | DNA processing chain A; High confidence in function and specificity. | Hypothetical protein predicted by Glimmer/Critica. | 0.417 |
| dprA | topA | sce5116 | sce5115 | DNA processing chain A; High confidence in function and specificity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.757 |
| gid | dprA | sce5114 | sce5116 | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | DNA processing chain A; High confidence in function and specificity. | 0.536 |
| gid | sce5117 | sce5114 | sce5117 | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | No similarity. | 0.407 |
| gid | topA | sce5114 | sce5115 | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
| glpQ | sce5117 | sce5119 | sce5117 | Glycerophosphodiester phosphodiesterase; Family membership. | No similarity. | 0.401 |
| glpQ | sce5118 | sce5119 | sce5118 | Glycerophosphodiester phosphodiesterase; Family membership. | Hypothetical protein predicted by Glimmer/Critica. | 0.776 |
| sce5117 | dprA | sce5117 | sce5116 | No similarity. | DNA processing chain A; High confidence in function and specificity. | 0.714 |
| sce5117 | gid | sce5117 | sce5114 | No similarity. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.407 |
| sce5117 | glpQ | sce5117 | sce5119 | No similarity. | Glycerophosphodiester phosphodiesterase; Family membership. | 0.401 |
| sce5117 | sce5118 | sce5117 | sce5118 | No similarity. | Hypothetical protein predicted by Glimmer/Critica. | 0.401 |
| sce5117 | topA | sce5117 | sce5115 | No similarity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.463 |
| sce5118 | dprA | sce5118 | sce5116 | Hypothetical protein predicted by Glimmer/Critica. | DNA processing chain A; High confidence in function and specificity. | 0.417 |
| sce5118 | glpQ | sce5118 | sce5119 | Hypothetical protein predicted by Glimmer/Critica. | Glycerophosphodiester phosphodiesterase; Family membership. | 0.776 |
| sce5118 | sce5117 | sce5118 | sce5117 | Hypothetical protein predicted by Glimmer/Critica. | No similarity. | 0.401 |
| sce5118 | topA | sce5118 | sce5115 | Hypothetical protein predicted by Glimmer/Critica. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.416 |
| topA | dprA | sce5115 | sce5116 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | DNA processing chain A; High confidence in function and specificity. | 0.757 |
| topA | gid | sce5115 | sce5114 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.932 |