STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sce7307TPP_enzyme_C domain-containing protein; Unnamed protein product; Family membership. (187 aa)    
Predicted Functional Partners:
comD
ComD protein; Family membership.
  
  0.999
pepM
Phosphoenolpyruvate mutase; High confidence in function and specificity.
  
 0.967
ilvN
Acetolactate synthase; Family membership.
  
 
 0.937
sce7308
Sugar nucleotidyltransferase; Family membership.
 
     0.915
leuC2
3-isopropylmalate dehydratase; Family membership.
  
  
 0.819
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.644
sce9323
Hypothetical protein predicted by Glimmer/Critica.
  
  
 0.610
phnW
2-aminoethylphosphonate:pyruvate aminotransferase; Family membership.
 
 
 0.608
sce6079
Putative nucleotidyl transferase; Specificity unclear.
 
     0.533
ilvD1
Dihydroxy-acid dehydratase; High confidence in function and specificity; Belongs to the IlvD/Edd family.
  
  
 0.521
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.