STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxA3Thioredoxin; High confidence in function and specificity; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
trxB
Thioredoxin-disulfide reductase; High confidence in function and specificity.
 
 
 0.843
sce8790
Pyridine nucleotide-disulphide oxidoreductase,class II; Family membership.
  
 
 0.803
cysH
Phosphoadenylyl-sulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
    
 
 0.737
gap
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.654
grpE
Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
  
 0.547
tlpA
Thiol:disulfide interchange protein tlpA; Family membership.
 
   
 0.547
sce4344
Hypothetical protein, similar to thioredoxin reductase.
  
 
 0.547
tpi
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.544
gltB1
Glutamate synthase (NADPH); High confidence in function and specificity.
   
 
 0.511
arsC2
Arsenate reductase (glutaredoxin); Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.496
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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