BWQ96_06122 protein (Gracilariopsis chorda) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BWQ96_06122

Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (621 aa)

Predicted Functional Partners:

BWQ96_09012

0.734

BWQ96_01196

0.727

BWQ96_05611

0.723

BWQ96_06555

0.714

BWQ96_05696

0.712

BWQ96_01340

0.709

BWQ96_07175

0.707

BWQ96_03673

0.705

BWQ96_01341

0.704

BWQ96_04060

0.696

Your Current Organism:

Gracilariopsis chorda

NCBI taxonomy Id: 448386
Other names: G. chorda, Gracilaria chorda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BWQ96_01196	BWQ96_01340	A0A2V3J3S1	A0A2V3J327	30S ribosomal protein S6.	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	0.999
BWQ96_01196	BWQ96_01341	A0A2V3J3S1	A0A2V3J321	30S ribosomal protein S6.	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.998
BWQ96_01196	BWQ96_03673	A0A2V3J3S1	A0A2V3IWV1	30S ribosomal protein S6.	37S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family.	0.999
BWQ96_01196	BWQ96_04060	A0A2V3J3S1	A0A2V3IVS3	30S ribosomal protein S6.	50S ribosomal protein L19.	0.998
BWQ96_01196	BWQ96_05611	A0A2V3J3S1	A0A2V3IR75	30S ribosomal protein S6.	60S ribosomal protein L5.	0.998
BWQ96_01196	BWQ96_05696	A0A2V3J3S1	A0A2V3IQY4	30S ribosomal protein S6.	60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.	0.998
BWQ96_01196	BWQ96_06122	A0A2V3J3S1	A0A2V3IQ14	30S ribosomal protein S6.	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	0.727
BWQ96_01196	BWQ96_06555	A0A2V3J3S1	A0A2V3INR3	30S ribosomal protein S6.	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.999
BWQ96_01196	BWQ96_07175	A0A2V3J3S1	A0A2V3IM04	30S ribosomal protein S6.	40S ribosomal protein S3-B; Belongs to the universal ribosomal protein uS3 family.	0.998
BWQ96_01196	BWQ96_09012	A0A2V3J3S1	A0A2V3IGS1	30S ribosomal protein S6.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.550
BWQ96_01340	BWQ96_01196	A0A2V3J327	A0A2V3J3S1	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	30S ribosomal protein S6.	0.999
BWQ96_01340	BWQ96_01341	A0A2V3J327	A0A2V3J321	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.999
BWQ96_01340	BWQ96_03673	A0A2V3J327	A0A2V3IWV1	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	37S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family.	0.999
BWQ96_01340	BWQ96_04060	A0A2V3J327	A0A2V3IVS3	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	50S ribosomal protein L19.	0.998
BWQ96_01340	BWQ96_05611	A0A2V3J327	A0A2V3IR75	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L5.	0.998
BWQ96_01340	BWQ96_05696	A0A2V3J327	A0A2V3IQY4	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.	0.998
BWQ96_01340	BWQ96_06122	A0A2V3J327	A0A2V3IQ14	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	0.709
BWQ96_01340	BWQ96_06555	A0A2V3J327	A0A2V3INR3	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.999
BWQ96_01340	BWQ96_07175	A0A2V3J327	A0A2V3IM04	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S3-B; Belongs to the universal ribosomal protein uS3 family.	0.999
BWQ96_01340	BWQ96_09012	A0A2V3J327	A0A2V3IGS1	40S ribosomal protein S14-3; Belongs to the universal ribosomal protein uS11 family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.811

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.858

expected number of edges:

15

PPI enrichment p-value:

0.00815

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006541

Glutamine metabolic process

3 of 11

1.91

1.05

0.0092

GO:0006528

Asparagine metabolic process

2 of 3

2.3

0.97

0.0166

GO:1901605

Alpha-amino acid metabolic process

5 of 120

1.1

0.73

0.0105

GO:0006520

Cellular amino acid metabolic process

6 of 171

1.02

0.69

0.0092

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016884

Carbon-nitrogen ligase activity, with glutamine as amido-N-donor

3 of 9

2.0

1.28

0.0033

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

4 of 35

1.53

1.12

0.0033

GO:0050567

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

2 of 3

2.3

0.98

0.0159

GO:0016874

Ligase activity

5 of 88

1.23

0.94

0.0033

GO:0097367

Carbohydrate derivative binding

7 of 474

0.64

0.4

0.0274

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1317

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, and tRNA synthetases class II (D, K and N)

4 of 5

2.38

2.71

6.20e-06

CL:140

Mixed, incl. Glycine catabolic process, and Oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

3 of 14

1.81

1.17

0.0045

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00250

Alanine, aspartate and glutamate metabolism

5 of 21

1.85

2.62

1.03e-06

map00970

Aminoacyl-tRNA biosynthesis

3 of 36

1.4

0.9

0.0089

map01100

Metabolic pathways

10 of 1027

0.46

0.36

0.0041

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030956

glutamyl-tRNA(Gln) amidotransferase complex

2 of 2

2.48

0.99

0.0157

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0436

Ligase

5 of 70

1.33

1.23

0.00045

KW-0648

Protein biosynthesis

4 of 48

1.4

1.13

0.0017

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About