node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BWQ96_00293 | BWQ96_00298 | A0A2V3J781 | A0A2V3J6T6 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Crossover junction endonuclease MUS81. | 0.656 |
BWQ96_00293 | BWQ96_02506 | A0A2V3J781 | A0A2V3J095 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Tyrosyl-DNA phosphodiesterase 1. | 0.900 |
BWQ96_00293 | BWQ96_02537 | A0A2V3J781 | A0A2V3J019 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA cross-link repair 1A protein. | 0.594 |
BWQ96_00293 | BWQ96_02705 | A0A2V3J781 | A0A2V3IZJ4 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA repair endonuclease XPF. | 0.481 |
BWQ96_00293 | BWQ96_03964 | A0A2V3J781 | A0A2V3IVY5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA ligase 4. | 0.435 |
BWQ96_00293 | BWQ96_04859 | A0A2V3J781 | A0A2V3ITA8 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Uncharacterized protein. | 0.563 |
BWQ96_00293 | BWQ96_04897 | A0A2V3J781 | A0A2V3IUI3 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | X-ray repair cross-complementing protein 5. | 0.482 |
BWQ96_00293 | BWQ96_07478 | A0A2V3J781 | A0A2V3IL10 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | ATP-dependent DNA helicase 2 subunit KU80. | 0.464 |
BWQ96_00293 | BWQ96_08449 | A0A2V3J781 | A0A2V3IL17 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin and WLM domain-containing metalloprotease. | 0.508 |
BWQ96_00298 | BWQ96_00293 | A0A2V3J6T6 | A0A2V3J781 | Crossover junction endonuclease MUS81. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.656 |
BWQ96_00298 | BWQ96_02506 | A0A2V3J6T6 | A0A2V3J095 | Crossover junction endonuclease MUS81. | Tyrosyl-DNA phosphodiesterase 1. | 0.626 |
BWQ96_00298 | BWQ96_02537 | A0A2V3J6T6 | A0A2V3J019 | Crossover junction endonuclease MUS81. | DNA cross-link repair 1A protein. | 0.772 |
BWQ96_00298 | BWQ96_02705 | A0A2V3J6T6 | A0A2V3IZJ4 | Crossover junction endonuclease MUS81. | DNA repair endonuclease XPF. | 0.921 |
BWQ96_00298 | BWQ96_03964 | A0A2V3J6T6 | A0A2V3IVY5 | Crossover junction endonuclease MUS81. | DNA ligase 4. | 0.506 |
BWQ96_00298 | BWQ96_04897 | A0A2V3J6T6 | A0A2V3IUI3 | Crossover junction endonuclease MUS81. | X-ray repair cross-complementing protein 5. | 0.522 |
BWQ96_00298 | BWQ96_07478 | A0A2V3J6T6 | A0A2V3IL10 | Crossover junction endonuclease MUS81. | ATP-dependent DNA helicase 2 subunit KU80. | 0.504 |
BWQ96_02506 | BWQ96_00293 | A0A2V3J095 | A0A2V3J781 | Tyrosyl-DNA phosphodiesterase 1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.900 |
BWQ96_02506 | BWQ96_00298 | A0A2V3J095 | A0A2V3J6T6 | Tyrosyl-DNA phosphodiesterase 1. | Crossover junction endonuclease MUS81. | 0.626 |
BWQ96_02506 | BWQ96_02537 | A0A2V3J095 | A0A2V3J019 | Tyrosyl-DNA phosphodiesterase 1. | DNA cross-link repair 1A protein. | 0.800 |
BWQ96_02506 | BWQ96_02705 | A0A2V3J095 | A0A2V3IZJ4 | Tyrosyl-DNA phosphodiesterase 1. | DNA repair endonuclease XPF. | 0.745 |