STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepPXaa-Pro aminopeptidase. (435 aa)    
Predicted Functional Partners:
LHA_0063
2-polyprenyl-6-methoxyphenol hydroxylase.
 
  
 0.911
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
  
 0.900
LHA_0060
Homologs of previously reported genes of unknown function; Belongs to the UPF0149 family.
 
   
 0.852
LHA_0059
Conserved protein of unknown function; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.770
hisS
Histidyl-tRNA synthetase.
  
 
 0.607
LHA_0065
Homologs of previously reported genes of unknown function.
       0.604
LHA_0067
ABC transporter, ATP binding protein.
       0.604
LHA_0066
Homologs of previously reported genes of unknown function.
       0.592
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
   
 
 0.479
LHA_1995
Beta-ketoacyl synthase (fragment).
   
 
 0.479
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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