Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (624 aa)    
Predicted Functional Partners:
iolE
Inosose dehydratase.
 
 
 0.998
iolCB
IolC/IolB transferase kinase protein.
 
  
 0.991
yrbE
Uncharacterized oxidoreductase yrbE.
 
  
 0.977
LHA_0077
D-xylose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
 0.892
LHA_0442
Acetolactate synthase; Belongs to the TPP enzyme family.
  
  
 
0.586
alsS
Acetolactate synthase; Belongs to the TPP enzyme family.
  
  
 
0.583
LHA_0076
Protein of unknown function; No homology to any previously reported sequences.
       0.525
iolA
Methylmalonate semialdehyde dehydrogenase [acylating].
 
  
 0.510
LHA_1168
Oxidoreductase; Function of strongly homologous gene; enzyme.
 
  
 0.467
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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