LHA_0178 protein (Legionella hackeliae) - STRING interaction network

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Score

LHA_0178

Membrane protein of unknown function; No homology to any previously reported sequences. (177 aa)

Predicted Functional Partners:

queC

0.571

metG

0.539

LHA_0180

0.532

nth

0.527

LHA_0176

0.481

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_0176	LHA_0178	LHA_0176	LHA_0178	Protein of unknown function; No homology to any previously reported sequences.	Membrane protein of unknown function; No homology to any previously reported sequences.	0.481
LHA_0176	queC	LHA_0176	LHA_0177	Protein of unknown function; No homology to any previously reported sequences.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.732
LHA_0178	LHA_0176	LHA_0178	LHA_0176	Membrane protein of unknown function; No homology to any previously reported sequences.	Protein of unknown function; No homology to any previously reported sequences.	0.481
LHA_0178	LHA_0180	LHA_0178	LHA_0180	Membrane protein of unknown function; No homology to any previously reported sequences.	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	0.532
LHA_0178	metG	LHA_0178	LHA_0179	Membrane protein of unknown function; No homology to any previously reported sequences.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.539
LHA_0178	nth	LHA_0178	LHA_0181	Membrane protein of unknown function; No homology to any previously reported sequences.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.527
LHA_0178	queC	LHA_0178	LHA_0177	Membrane protein of unknown function; No homology to any previously reported sequences.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.571
LHA_0180	LHA_0178	LHA_0180	LHA_0178	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	Membrane protein of unknown function; No homology to any previously reported sequences.	0.532
LHA_0180	metG	LHA_0180	LHA_0179	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.866
LHA_0180	nth	LHA_0180	LHA_0181	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.874
LHA_0180	queC	LHA_0180	LHA_0177	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.419
metG	LHA_0178	LHA_0179	LHA_0178	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Membrane protein of unknown function; No homology to any previously reported sequences.	0.539
metG	LHA_0180	LHA_0179	LHA_0180	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	0.866
metG	nth	LHA_0179	LHA_0181	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.852
metG	queC	LHA_0179	LHA_0177	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.449
nth	LHA_0178	LHA_0181	LHA_0178	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	Membrane protein of unknown function; No homology to any previously reported sequences.	0.527
nth	LHA_0180	LHA_0181	LHA_0180	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.	0.874
nth	metG	LHA_0181	LHA_0179	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.852
nth	queC	LHA_0181	LHA_0177	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.463
queC	LHA_0176	LHA_0177	LHA_0176	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	Protein of unknown function; No homology to any previously reported sequences.	0.732