Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0211Homologs of previously reported genes of unknown function. (146 aa)    
Predicted Functional Partners:
LHA_0210
Conserved protein of unknown function; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.743
LHA_0212
Putative Cyclin-dependent kinase [Serine/threonine-protein kinase-like domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.466
LHA_3105
Homologs of previously reported genes of unknown function.
       0.461
LHA_3107
Homologs of previously reported genes of unknown function.
       0.461
LHA_3108
Homologs of previously reported genes of unknown function.
       0.461
LHA_3109
Homologs of previously reported genes of unknown function.
       0.461
LHA_3110
Homologs of previously reported genes of unknown function.
       0.461
LHA_3111
ATPase associated with various cellular activities, AAA_3; Function of strongly homologous gene; enzyme.
       0.410
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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