Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
vipFN-terminal acetyltransferase, GNAT family; Function of strongly homologous gene; enzyme. (291 aa)    
Predicted Functional Partners:
AnkH
Substrate of the Dot/Icm secretion system [ankyrin repeat]; Function of strongly homologous gene; factor.
  
   
 0.733
LHA_0221
Putative arginine-binding periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the bacterial solute-binding protein 3 family.
       0.569
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
       0.550
LHA_0224
Protein of unknown function; No homology to any previously reported sequences.
       0.531
yicO
Xanthine/uracil permease; Function of strongly homologous gene; transporter.
       0.461
LHA_0226
Homologs of previously reported genes of unknown function.
       0.461
LHA_0220
Protein of unknown function; No homology to any previously reported sequences.
       0.441
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.409
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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