STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0312Glucose-1-phosphate thymidylyltransferase; Function of strongly homologous gene; enzyme. (218 aa)    
Predicted Functional Partners:
LHA_0313
Aminoglycoside phosphotransferase involved in cell wall biosynthesis; Function of strongly homologous gene; enzyme.
 
 
 0.995
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
    
  0.901
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
0.833
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
 0.803
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
     
  0.800
rmlB
dTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.792
lptD
LPS-assembly protein lptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
     0.655
xanB
Xanthan biosynthesis protein xanB [Includes: Mannose-6-phosphate isomerase; Mannose-1-phosphate guanylyl transferase]; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.618
LHA_1162
NAD-dependent epimerase/dehydratase.
 
 
 0.545
surA
Chaperone surA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
  
   0.500
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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