Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
argRPutative arginine repressor; Regulates arginine biosynthesis genes. (152 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.968
argH
Argininosuccinate lyase.
  
  
 0.965
argD
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.830
tcyN
L-cystine import ATP-binding protein TcyN.
 
   
 0.789
glnP
Putative glutamine transport system permease protein glnP; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.686
yqiX
Amino acid (Glutamine) ABC transporter, periplasmic amino acid binding protein; Belongs to the bacterial solute-binding protein 3 family.
 
   
 0.661
birA
Biotin synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.651
LHA_1409
TrpR-like protein.
  
     0.505
LHA_2213
Flagellar protein FliJ.
   
  
 0.490
LHA_2837
Uncharacterized protein; Gene remnant;/product='fragment of Integrase/recombinase XerD, putative'.
  
     0.417
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (22%) [HD]