STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gorGlutathione reductase. (449 aa)    
Predicted Functional Partners:
LHA_2872
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 0.997
bsaA
Glutathione peroxidase homolog BsaA; Belongs to the glutathione peroxidase family.
  
 0.940
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.935
ggt
Gamma-glutamyltranspeptidase.
     
 0.923
gst
Glutathione S-transferase.
  
 0.922
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.865
aceF
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.842
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.816
LHA_1574
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.806
LHA_0474
Putative transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.803
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.