STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0554Protein of unknown function; No homology to any previously reported sequences. (598 aa)    
Predicted Functional Partners:
LHA_1423
Protein of unknown function [Cytochrome P450 domain]; No homology to any previously reported sequences; Belongs to the cytochrome P450 family.
  
     0.743
comA
Phosphosulfolactate synthase; Function of strongly homologous gene; enzyme.
  
     0.685
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
 
     0.520
LHA_0853
Acid phosphatase; Function of strongly homologous gene; enzyme.
  
     0.496
LHA_2913
Protein of unknown function; No homology to any previously reported sequences.
  
     0.464
LHA_0488
Homologs of previously reported genes of unknown function.
  
     0.456
LHA_1344
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
  
     0.456
nudE
ADP-ribose diphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.447
LHA_0503
Putative 2,4-dichlorophenol 6-monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.445
LHA_2288
Truncated thermolabile hemolysin.
  
     0.443
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.