STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0563Homologs of previously reported genes of unknown function. (91 aa)    
Predicted Functional Partners:
silP
Putative cation-transporting P-type ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.918
LHA_0559
Chemiosmotic efflux system protein A-like protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.866
cecB
Chemiosmotic efflux system C protein B; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.828
cecC
Chemiosmotic efflux system C protein C.
       0.773
LHA_0558
Homologs of previously reported genes of unknown function.
       0.703
LHA_0564
CBS domain protein.
  
    0.554
LHA_0557
Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.461
LHA_0664
Copper-exporting ATPase; Function of strongly homologous gene.
 
  
 0.436
fliA
RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
    
   0.420
LHA_2261
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
    
   0.420
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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