Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0585Putative PTS IIA-like nitrogen-regulatory protein PtsN; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (156 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr.
 
 
 0.996
yhbH
Ribosome-associated, sigma 54 modulation protein; Function of strongly homologous gene; factor.
 
  
 0.965
ptsP
Phosphoenolpyruvate-protein phosphotransferase ptsP; Belongs to the PEP-utilizing enzyme family.
  
   
 0.834
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.814
LHA_0294
Sigma 54 modulation protein YhbH.
  
  
 0.568
LHA_0584
Homologs of previously reported genes of unknown function.
       0.484
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
    0.454
LHA_0589
Protein of unknown function; Doubtful CDS.
       0.452
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.433
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.430
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: medium (56%) [HD]