Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cinACompetence-damage inducible protein; Function of strongly homologous gene; regulator. (365 aa)    
Predicted Functional Partners:
CinA
Competence-damage inducible protein CinA; Function of strongly homologous gene; cell process; Belongs to the CinA family.
   
 0.931
LHA_0627
Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.866
LHA_0628
Putative MscS mechanosensitive ion channel; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.866
LHA_1317
Homologs of previously reported genes of unknown function.
      
 0.624
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.534
LHA_0629
Putative effector protein B (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.513
LHA_0635
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
       0.442
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.442
nadE
Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.418
icd
Isocitrate dehydrogenase [NADP].
      0.414
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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