STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0647Conserved protein of unknown function; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (201 aa)    
Predicted Functional Partners:
LHA_0648
Transporter, Zip family.
       0.803
LHA_0652
tRNA methyl transferase-like protein.
  
    0.794
LHA_0651
Homologs of previously reported genes of unknown function; Belongs to the sulfur carrier protein TusA family.
  
    0.793
LHA_0650
Homologs of previously reported genes of unknown function; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.791
LHA_0490
Homologs of previously reported genes of unknown function; Belongs to the UPF0758 family.
  
  
 0.789
hprA
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.789
LHA_0646
Putative patatin-like phospholipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.541
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.499
hisI
Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family.
      
 0.436
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
   
 
 0.419
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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