Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_0664Copper-exporting ATPase; Function of strongly homologous gene. (881 aa)    
Predicted Functional Partners:
LHA_0663
Homologs of previously reported genes of unknown function.
       0.615
argS
Arginyl-tRNA synthetase.
       0.613
cueO
Multicopper oxidase; Function of strongly homologous gene; enzyme.
 
  
 0.479
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.464
LHA_0563
Homologs of previously reported genes of unknown function.
 
  
 0.436
LHA_0650
Homologs of previously reported genes of unknown function; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
 0.434
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.434
LHA_0194
Transcriptional regulator, ArsR family.
  
  
 0.432
LHA_2777
Cation efflux system protein, CDF family.
  
  
 0.411
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (20%) [HD]