yicC protein (Legionella hackeliae) - STRING interaction network

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[Homology]

Score

yicC

Homologs of previously reported genes of unknown function. (284 aa)

Predicted Functional Partners:

gmk

0.959

rph

0.746

rpoZ

0.735

spoT

0.602

tdcF

0.602

LHA_0701

0.577

yggS

0.514

pheA

0.423

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_0701	gmk	LHA_0701	LHA_0697	Aspartyl protease; Function of strongly homologous gene; enzyme.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.573
LHA_0701	rpoZ	LHA_0701	LHA_0698	Aspartyl protease; Function of strongly homologous gene; enzyme.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.648
LHA_0701	spoT	LHA_0701	LHA_0699	Aspartyl protease; Function of strongly homologous gene; enzyme.	Bifunctional (p)ppGpp synthase/hydrolase SpoT [Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.780
LHA_0701	tdcF	LHA_0701	LHA_0700	Aspartyl protease; Function of strongly homologous gene; enzyme.	L-PSP (mRNA) endoribonuclease; Function of strongly homologous gene; enzyme.	0.780
LHA_0701	yicC	LHA_0701	LHA_0696	Aspartyl protease; Function of strongly homologous gene; enzyme.	Homologs of previously reported genes of unknown function.	0.577
gmk	LHA_0701	LHA_0697	LHA_0701	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Aspartyl protease; Function of strongly homologous gene; enzyme.	0.573
gmk	rph	LHA_0697	LHA_0695	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.759
gmk	rpoZ	LHA_0697	LHA_0698	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.939
gmk	spoT	LHA_0697	LHA_0699	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Bifunctional (p)ppGpp synthase/hydrolase SpoT [Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.965
gmk	tdcF	LHA_0697	LHA_0700	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	L-PSP (mRNA) endoribonuclease; Function of strongly homologous gene; enzyme.	0.637
gmk	yggS	LHA_0697	LHA_0694	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.	0.411
gmk	yicC	LHA_0697	LHA_0696	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Homologs of previously reported genes of unknown function.	0.959
pheA	rpoZ	LHA_0936	LHA_0698	P-protein [Includes: Chorismate mutase; Prephenate dehydratase].	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.478
pheA	yicC	LHA_0936	LHA_0696	P-protein [Includes: Chorismate mutase; Prephenate dehydratase].	Homologs of previously reported genes of unknown function.	0.423
rph	gmk	LHA_0695	LHA_0697	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.759
rph	rpoZ	LHA_0695	LHA_0698	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.698
rph	spoT	LHA_0695	LHA_0699	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Bifunctional (p)ppGpp synthase/hydrolase SpoT [Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.612
rph	tdcF	LHA_0695	LHA_0700	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	L-PSP (mRNA) endoribonuclease; Function of strongly homologous gene; enzyme.	0.727
rph	yggS	LHA_0695	LHA_0694	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Putative enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.	0.627
rph	yicC	LHA_0695	LHA_0696	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Homologs of previously reported genes of unknown function.	0.746