Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metNMethionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)    
Predicted Functional Partners:
metQ
D-methionine-binding lipoprotein metQ.
 
 0.999
metI
Putative D-methionine transport system permease protein metI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.999
aprD
Alkaline protease secretion ATP-binding protein AprD.
 
     
0.763
LHA_0068
ABC transporter, permease.
 
     0.717
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.700
LHA_0767
Protein of unknown function; No homology to any previously reported sequences.
       0.663
LHA_0478
Export ABC transporter permease protein.
 
      0.475
LHA_2083
Putative ABC transporter ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     
0.467
LHA_3231
Putative ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    
0.453
metC
Cystathionine beta-lyase.
  
  
 0.447
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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