STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsA-2Acetoacetyl-coenzyme A synthetase [putative SET domain]; Function of strongly homologous gene; enzyme. (646 aa)    
Predicted Functional Partners:
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.973
phbA
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.964
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein/.
 
 0.955
yfcX
YfcX enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.948
LHA_0914
Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
LHA_1543
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
adc
Putative acetoacetate decarboxylase 2; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.
     
  0.900
LHA_0923
3-hydroxybutyrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.900
phbB
Acetoacetyl-CoA reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator;/product='putative Polyhydroxyalkanoate synthesis repressor PhaR (fragment)'.
    
  0.900
phbB-2
Acetoacetyl-CoA reductase.
    
  0.900
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.