STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsA-2Acetoacetyl-coenzyme A synthetase [putative SET domain]; Function of strongly homologous gene; enzyme. (646 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein/.
 
 0.988
yfcX
YfcX enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.985
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.962
phbA
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.953
LHA_0914
Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
LHA_1543
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
LHA_0923
3-hydroxybutyrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.902
phbB
Acetoacetyl-CoA reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator;/product='putative Polyhydroxyalkanoate synthesis repressor PhaR (fragment)'.
   
 0.902
phbB-2
Acetoacetyl-CoA reductase.
   
 0.902
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 
 0.844
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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