Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tolCOuter membrane protein TolC. (553 aa)    
Predicted Functional Partners:
LHA_1489
Homologs of previously reported genes of unknown function; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.959
acrA
Acriflavine resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.959
acrA-2
RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.959
LHA_0688
Putative HlyD-like secretion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.957
LHA_0687
Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.931
bepG
Efflux pump membrane transporter BepG.
  
 0.931
LHA_1488
Homologs of previously reported genes of unknown function; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.931
acrB
Acriflavine resistance protein B.
  
 0.931
LHA_2330
Uncharacterized transporter HI_0895; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.931
LHA_0791
Putative RND efflux system, outer membrane lipoprotein, NodT; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.914
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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