STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adcPutative acetoacetate decarboxylase 2; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family. (245 aa)    
Predicted Functional Partners:
LHA_0923
3-hydroxybutyrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
  0.986
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
  0.900
acsA-2
Acetoacetyl-coenzyme A synthetase [putative SET domain]; Function of strongly homologous gene; enzyme.
     
  0.800
LHA_1495
Putative patatin-like phospholipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.745
LHA_0646
Putative patatin-like phospholipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.731
motB
Motility protein B.
       0.654
motA
Motility protein A.
       0.654
LHA_2287
Putative proline-rich exported protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.512
LHA_0288
ABC transporter, permease protein.
  
     0.506
LHA_0661
Homologs of previously reported genes of unknown function.
 
   
 0.498
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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