LHA_0976 protein (Legionella hackeliae) - STRING interaction network

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LHA_0976

Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease. (569 aa)

Predicted Functional Partners:

lepA

0.489

mltB

0.482

lspL

0.430

LHA_2609

0.410

LHA_0508

0.409

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_0508	LHA_0976	LHA_0508	LHA_0976	Putative Phenylalanine racemase (ATP-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	0.409
LHA_0508	LHA_2609	LHA_0508	LHA_2609	Putative Phenylalanine racemase (ATP-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
LHA_0976	LHA_0508	LHA_0976	LHA_0508	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	Putative Phenylalanine racemase (ATP-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.409
LHA_0976	LHA_2609	LHA_0976	LHA_2609	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.410
LHA_0976	lepA	LHA_0976	LHA_0977	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.489
LHA_0976	lspL	LHA_0976	LHA_0974	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	0.430
LHA_0976	mltB	LHA_0976	LHA_0975	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	Membrane-bound lytic murein transglycosylase B.	0.482
LHA_2609	LHA_0508	LHA_2609	LHA_0508	Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Phenylalanine racemase (ATP-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
LHA_2609	LHA_0976	LHA_2609	LHA_0976	Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	0.410
lepA	LHA_0976	LHA_0977	LHA_0976	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	0.489
lepA	lspL	LHA_0977	LHA_0974	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	0.579
lepA	mltB	LHA_0977	LHA_0975	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	Membrane-bound lytic murein transglycosylase B.	0.615
lspL	LHA_0976	LHA_0974	LHA_0976	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	0.430
lspL	lepA	LHA_0974	LHA_0977	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.579
lspL	mltB	LHA_0974	LHA_0975	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	Membrane-bound lytic murein transglycosylase B.	0.743
mltB	LHA_0976	LHA_0975	LHA_0976	Membrane-bound lytic murein transglycosylase B.	Virulence metalloprotease precursor (Vibriolysin); Extracellular zinc metalloprotease.	0.482
mltB	lepA	LHA_0975	LHA_0977	Membrane-bound lytic murein transglycosylase B.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.615
mltB	lspL	LHA_0975	LHA_0974	Membrane-bound lytic murein transglycosylase B.	Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.	0.743