Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gabD1Succinate-semialdehyde dehydrogenase (NAD(P)(+)); Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (463 aa)    
Predicted Functional Partners:
LHA_0981
Putative alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.944
glnA
Type-1 glutamine synthetase 2.
 
  
 0.943
LHA_0980
Putative glutamine amidotransferase, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.858
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
      0.716
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.670
yfcX
YfcX enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.600
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein/.
  
 0.600
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 
 0.595
LHA_1995
Beta-ketoacyl synthase (fragment).
  
 
 0.595
LHA_0984
Protein of unknown function; No homology to any previously reported sequences.
       0.476
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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