STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnAType-1 glutamine synthetase 2. (457 aa)    
Predicted Functional Partners:
LHA_0981
Putative alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.949
gabD1
Succinate-semialdehyde dehydrogenase (NAD(P)(+)); Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
 
  
 0.943
putA
Bifunctional protein putA [Includes: Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.928
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
  
 0.926
glsA
Glutaminase; Belongs to the glutaminase family.
    
 0.926
LHA_1560
NAD-glutamate dehydrogenase; Function of strongly homologous gene; enzyme.
     
 0.925
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.923
glnA-2
Glutamine synthetase.
  
  
 
0.920
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
 
 0.916
LHA_0499
Putative 2-aminoadipate transaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.903
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.