Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhS-(hydroxymethyl)glutathione dehydrogenase. (390 aa)    
Predicted Functional Partners:
LHA_0987
Putative Hemerythrin HHE cation binding domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.821
yhxC
Uncharacterized oxidoreductase yhxC.
 
    0.690
LHA_2010
DNA topoisomerase; Function of strongly homologous gene; enzyme.
  
     0.552
LHA_2008
Putative FAD dependent oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.548
LHA_0507
Protein of unknown function; No homology to any previously reported sequences; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.516
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
  
 0.434
LHA_1995
Beta-ketoacyl synthase (fragment).
  
  
 0.434
LHA_2872
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
  
 0.434
LHA_0985
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.417
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.417
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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