Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pilZType IV pilus assembly PilZ; Function of strongly homologous gene. (185 aa)    
Predicted Functional Partners:
fliS
B-type flagellar protein fliS.
 
  
 0.884
LHA_1845
Conserved protein of unknown function; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.878
LHA_2029
Homologs of previously reported genes of unknown function; Belongs to the flagella basal body rod proteins family.
 
  
 0.815
LHA_1413
Putative flagella synthesis protein FlgN; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
  
 0.804
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
   0.804
LHA_2213
Flagellar protein FliJ.
 
    0.785
LHA_2687
Homologs of previously reported genes of unknown function.
  
     0.765
LHA_1354
Putative coiled-coil protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.762
iraA
Small-molecule methyltransferase IraA; Function of strongly homologous gene; enzyme.
  
     0.759
LHA_2164
Putative DamX-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.758
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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