STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LHA_1132Putative (2E,6E)-farnesyl diphosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the FPP/GGPP synthase family. (279 aa)    
Predicted Functional Partners:
LHA_1130
Phytoene synthase; Function of strongly homologous gene; enzyme.
  
 0.977
ispB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 0.933
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
 
 
 0.931
LHA_0635
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
  
  0.922
crtI
Phytoene dehydrogenase.
  
  
 0.844
LHA_1129
Lycopene cyclase; Function of strongly homologous gene; enzyme.
  
 
 0.825
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 0.822
LHA_1128
Membrane protein of unknown function [Beta-carotene 15,15'-monooxygenase, Brp/Blh family]; Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal. Belongs to the Brp/Blh beta-carotene diooxygenase family.
 
     0.814
LHA_1133
Xanthorhodopsin; Function of strongly homologous gene; enzyme.
       0.599
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 
 0.582
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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