Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_1165Sialic acid synthase. (358 aa)    
Predicted Functional Partners:
LHA_1169
CMP-N-acetylneuraminic acid synthetase.
 
 0.997
LHA_1164
UDP-N-acetylglucosamine 2-epimerase.
 
  
 0.974
LHA_1163
Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.970
LHA_1162
NAD-dependent epimerase/dehydratase.
 
    0.951
LHA_1167
Similar to Nucleotidyl transferase.
 
  
 0.932
LHA_1166
Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family.
 
     0.927
LHA_1171
Homologs of previously reported genes of unknown function.
 
   
 0.907
LHA_1170
Flagellin modification protein A.
 
     0.776
LHA_1168
Oxidoreductase; Function of strongly homologous gene; enzyme.
 
    0.734
hisH
Imidazole glycerol phosphate synthase subunit hisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
     
 0.725
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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