STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1170Flagellin modification protein A. (253 aa)    
Predicted Functional Partners:
LHA_1169
CMP-N-acetylneuraminic acid synthetase.
 
   0.899
LHA_1168
Oxidoreductase; Function of strongly homologous gene; enzyme.
 
    0.888
LHA_1167
Similar to Nucleotidyl transferase.
 
 
 0.879
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.802
LHA_1171
Homologs of previously reported genes of unknown function.
 
     0.782
LHA_1165
Sialic acid synthase.
 
    0.777
LHA_1174
Maltose O-acetyltransferase; Function of strongly homologous gene; enzyme.
 
  
 0.758
hisH
Imidazole glycerol phosphate synthase subunit hisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.711
hisF
Putative imidazole glycerol phosphate synthase subunit hisF2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the HisA/HisF family.
       0.708
LHA_1164
UDP-N-acetylglucosamine 2-epimerase.
 
    0.695
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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