Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LHA_1273Protein of unknown function; No homology to any previously reported sequences. (969 aa)    
Predicted Functional Partners:
LHA_1274
Type I secretion membrane fusion protein, HlyD; Function of strongly homologous gene; transporter.
 
    0.817
aprD
Alkaline protease secretion ATP-binding protein AprD.
 
 
 0.762
lssB
Legionella secretion system protein B.
 
  
 0.699
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.660
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
  
 0.659
LHA_1995
Beta-ketoacyl synthase (fragment).
  
  
 0.659
lssD
Legionella secretion system protein D.
 
    0.630
LHA_1317
Homologs of previously reported genes of unknown function.
  
  
 0.535
LHA_2487
Toxin secretion ABC transporter HlyB/MsbA family ATP-binding protein.
 
  
 0.489
LHA_2118
Type I secretion outer membrane protein, TolC family precursor; Function of strongly homologous gene; transporter.
  
  
 0.471
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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