STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprDAlkaline protease secretion ATP-binding protein AprD. (573 aa)    
Predicted Functional Partners:
LHA_1274
Type I secretion membrane fusion protein, HlyD; Function of strongly homologous gene; transporter.
  
 0.957
LHA_1273
Protein of unknown function; No homology to any previously reported sequences.
 
 
 0.777
metN
Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
     
0.763
LHA_1276
Conserved protein of unknown function [Hemolysin-type calcium-binding region]; Homologs of previously reported genes of unknown function.
 
 
 0.740
lssD
Legionella secretion system protein D.
  
 0.689
tolC
Outer membrane protein TolC.
  
  
 0.482
LHA_2111
Protein of unknown function; No homology to any previously reported sequences.
 
   
 0.429
LHA_2118
Type I secretion outer membrane protein, TolC family precursor; Function of strongly homologous gene; transporter.
 
  
 0.417
ribBA
Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
      
 0.410
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.