STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1276Conserved protein of unknown function [Hemolysin-type calcium-binding region]; Homologs of previously reported genes of unknown function. (898 aa)    
Predicted Functional Partners:
LHA_2435
Signal peptide protein.
   
    0.818
LHA_2433
Homologs of previously reported genes of unknown function; Belongs to the UPF0276 family.
   
    0.791
LHA_1274
Type I secretion membrane fusion protein, HlyD; Function of strongly homologous gene; transporter.
 
  
 0.777
aprD
Alkaline protease secretion ATP-binding protein AprD.
 
 
 0.740
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
  
 0.676
LHA_1995
Beta-ketoacyl synthase (fragment).
  
  
 0.676
lssB
Legionella secretion system protein B.
 
  
 0.626
LHA_2630
Type IV secretory protein VirB4 component.
  
    0.613
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.588
lssD
Legionella secretion system protein D.
 
  
 0.578
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.