Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_13073-hydroxyisobutyryl-CoA hydrolase; Function of strongly homologous gene; enzyme. (349 aa)    
Predicted Functional Partners:
mmsB
Putative 3-hydroxyisobutyrate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the HIBADH-related family.
  
 0.985
acad
Isobutyryl-CoA dehydrogenase, mitochondrial.
 
 0.944
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 0.937
LHA_1995
Beta-ketoacyl synthase (fragment).
  
 0.937
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.901
crt
3-hydroxybutyryl-CoA dehydratase.
 
   
0.879
LHA_0969
Sensory box histidine kinase/response regulator.
   
 0.830
LHA_2074
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 0.830
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 0.830
LHA_2313
Sensory box histidine kinase/response regulator (fragment).
   
 0.830
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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