Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1340Homologs of previously reported genes of unknown function. (250 aa)    
Predicted Functional Partners:
LHA_1341
Protein of unknown function; No homology to any previously reported sequences.
 
   
 0.783
LHA_1342
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.723
LHA_1339
Homologs of previously reported genes of unknown function.
     
 0.643
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
  
     0.549
LHA_1482
Polysaccharide deacetylase.
  
    0.475
LHA_3175
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
       0.461
LHA_1317
Homologs of previously reported genes of unknown function.
       0.454
LHA_1343
Putative Hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.446
LHA_0683
Putative polysaccharide deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.418
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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