Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
LHA_1504Sensor histidine kinase/response regulator LuxN. (417 aa)    
Predicted Functional Partners:
LHA_3158
PAS sensor histidine kinase domain protein.
 
 
 0.929
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.881
LHA_2313
Sensory box histidine kinase/response regulator (fragment).
 
 
 0.877
LHA_0969
Sensory box histidine kinase/response regulator.
 
 
 0.876
LHA_2074
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.876
LHA_2872
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.807
LHA_3062
Putative two-component system, fusion protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.807
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
     
 0.787
LHA_2338
Endo-1,3(4)-beta-glucanase; Function of strongly homologous gene; enzyme.
  
 
   0.761
LHA_2947
Serine/threonine-protein kinase; Function of strongly homologous gene; enzyme.
  
 
   0.757
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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