STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1531Tyrosine phosphatase II superfamily protein. (317 aa)    
Predicted Functional Partners:
LHA_2597
Protein of unknown function [coiled-coil domain]; No homology to any previously reported sequences.
   
 0.988
LHA_3171
Homologs of previously reported genes of unknown function.
   
 0.828
legA
Conserved protein of unknown function [ankyrin repeat]; Homologs of previously reported genes of unknown function.
  
 
  0.752
LHA_2342
Homologs of previously reported genes of unknown function.
  
 0.727
LHA_2721
Exported protein of unknown function; No homology to any previously reported sequences.
  
 
 0.707
lepA
GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.699
LHA_2566
Homologs of previously reported genes of unknown function.
  
     0.668
LHA_2481
Chitinase; Function of strongly homologous gene; enzyme.
  
     0.633
LHA_1152
Putative O-antigen ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.630
plaB
Phospholipase.
  
   
 0.630
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.