STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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[Homology]
Score
LHA_1554Putative Thioredoxin-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (185 aa)    
Predicted Functional Partners:
LHA_1553
Homologs of previously reported genes of unknown function.
       0.866
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
    0.729
LHA_1555
Homologs of previously reported genes of unknown function.
       0.703
LHA_1556
Homologs of previously reported genes of unknown function.
       0.703
LHA_1557
Putative phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.645
LHA_1177
Protein of unknown function; No homology to any previously reported sequences.
   
   0.577
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.577
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.563
gabD
Putative succinate-semialdehyde dehydrogenase [NADP+]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.550
LHA_1559
Homologs of previously reported genes of unknown function.
       0.550
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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