STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1562Homologs of previously reported genes of unknown function. (321 aa)    
Predicted Functional Partners:
LHA_1563
Homologs of previously reported genes of unknown function.
       0.615
LHA_1564
Protein of unknown function; No homology to any previously reported sequences.
       0.615
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
   
 0.581
apaH
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
  
     0.555
rpoE
RNA polymerase sigma-24 factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
       0.518
yadR
Putative chaperone involved in Fe-S cluster assembly and activation; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 0.518
iraA
Small-molecule methyltransferase IraA; Function of strongly homologous gene; enzyme.
  
     0.512
LHA_1039
Putative Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
  
   
 0.509
LHA_1898
Inner membrane protein AmpE.
  
     0.488
LHA_0403
Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.486
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.