STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1563Homologs of previously reported genes of unknown function. (84 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 
 0.965
LHA_1564
Protein of unknown function; No homology to any previously reported sequences.
       0.803
rpoE
RNA polymerase sigma-24 factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
       0.656
LHA_1562
Homologs of previously reported genes of unknown function.
       0.615
sdhC
Succinate dehydrogenase cytochrome b556 subunit.
 
   
 0.586
sdhB
Succinate dehydrogenase iron-sulfur subunit.
 
  
 0.546
yacG
Conserved protein of unknown function; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
  
     0.524
ruvB
Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.499
ybgC
acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.499
LHA_1570
Homologs of previously reported genes of unknown function.
 
     0.465
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.