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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (431 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.995
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.992
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.960
LHA_0507
Protein of unknown function; No homology to any previously reported sequences; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.929
LHA_0508
Putative Phenylalanine racemase (ATP-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.924
LHA_1602
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.873
LHA_1995
Beta-ketoacyl synthase (fragment).
 
  
 0.833
LHA_2073
6-deoxyerythronolide-B synthase; Function of strongly homologous gene; enzyme.
    
 0.829
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.813
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.800
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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