Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1632Homologs of previously reported genes of unknown function. (108 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine phosphoribosyltransferase.
       0.822
LHA_1631
Generic methyl-transferase.
       0.737
pilD
Type 4 prepilin-like proteins leader peptide-processing enzyme [Includes: Leader peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
       0.604
pilC
Type 4 fimbrial assembly protein pilC.
       0.604
pilB
Type 4 fimbrial assembly protein pilB.
       0.604
LHA_0105
Homologs of previously reported genes of unknown function.
  
     0.468
LHA_2168
Protein of unknown function; No homology to any previously reported sequences.
  
     0.457
LHA_1630
Protein of unknown function; No homology to any previously reported sequences.
       0.430
LHA_2280
Bacterial surface antigen; Function of strongly homologous gene; membrane component.
  
     0.406
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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