Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LHA_1640Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. (88 aa)    
Predicted Functional Partners:
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
  
 0.918
dacA
D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family.
  
    0.878
ala
Putative D-Ala-amino transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.868
lssY
Legionella secretion system protein Y.
       0.866
lssZ
LssZ protein.
       0.744
rlpA
Conserved protein of unknown function; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
    0.740
lssA
Legionella secretion system protein A.
       0.656
rlpA-2
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
    0.417
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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