STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
dacAD-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. (408 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.957
LHA_2880
Serine-type D-Ala-D-Ala carboxypeptidase; Function of strongly homologous gene; enzyme.
     
 0.955
ftsI
Peptidoglycan synthase ftsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 0.943
mrcA
Penicillin-binding protein 1A [Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase].
     
 0.927
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
     
 0.906
LHA_1640
Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family.
  
    0.878
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
    0.867
lssY
Legionella secretion system protein Y.
  
    0.866
ala
Putative D-Ala-amino transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.866
rlpA
Conserved protein of unknown function; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.801
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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